Genome-Wide SNP Genotyping Services

deCODE genetics has a continuing commitment to provide the scientific community with the most effective and comprehensive microsatellite and single nucleotide polymorphism (SNP) genotyping service available.

We have established a world leadership in providing genome-wide scans with microsatellites as well as customized fine mapping of loci with both microsatellites and SNPs. To provide a comprehensive one-stop solution for our clients we offer high-density genome-wide scans with SNPs. We operate a high-throughput CSPro laboratory for processing Illumina's all available BeadChips.

Our genome-wide association offering leverages our expertise in genotyping which our clients have learned to value and trust. Our industrial scale SNP genotyping laboratory will be able to return data to you with fast turn-around, without compromising on care and quality.

Whole-genome SNP genotyping technology

After evaluating competing technologies, deCODE chose the Illumina platform for its industry-leading per-sample genomic coverage and data quality. Our goal is to provide clients with the most reliable, accurate and information-rich method for performing genome-wide association studies.

The Illumina BeadChip uses the Infinium II Assay to capture hundreds of thousands of SNP and CNV loci in a single-tube whole-genome amplification method that does not require PCR. All BeadChips were specifically designed to include SNPs at even spacing across the genome and give preference to tagSNPs that have been identified as reliable proxies for an even larger pool of SNP loci.

Our high-throughput SNP laboratory features a large number of Illumina’s Bead Lab machines and dedicated high-throughput liquid handling robots for rapid data generation. All operations are highly automated. For quality assurance all plates, instruments and operators are labeled with barcodes allowing easy back-tracking and monitoring of performance. The LIMS software allows each sample and operation to be tracked through the sample handling process.

One-stop solution

deCODE provides you with detailed instructions as well as containers and barcode labels to prepare and ship your samples to our laboratories.

Once we have received your samples we verify the integrity of the DNA by genotyping a subset of your samples along with a reference sample. After verifying the test samples we process the rest of the samples and perform necessary steps for quality assurance on the resulting data.

You are informed by e-mail once your data is ready for release, and you have immediate access to the data on a secure FTP site. Your samples are handled throughout by our experienced team that is dedicated to quality and top-quality service. We put a premium on care in sample handling, data quality as well as fast turn-around.

For more information, please contact services@decode.com.